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The Lancet started as an independent, international weekly general medical journal established in 1823 by Thomas Wakley. Given that its very first issue (October 5, 1823), the journal has aimed to make science widely available so that medicine can serve, and change society, and favorably impact the lives of individuals. Over the previous two centuries, The Lancet has actually sought to address urgent topics in our society, start debate, put science into context, and influence decision makers around the globe.

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